My doctor said my labs are normal but I’m still exhausted. Are there other things to check?

Fatigue is one of the most common reasons people go to the doctor. As NDs, we talk about energy, or lack of, with patients everyday. Fatigue also has many different causes, so a thorough history, relevant physical exams, and laboratory testing are all indicated to help determine which causes are most likely relevant for you! 

Other symptoms that might provide helpful context and are important to tell your doctor about, if present, include: 

  • hair loss 

  • feeling cold all the time 

  • pale skin or easy bruising 

  • mood concerns like anxiety or depression 

  • frequent colds or flus 

  • weight change 

  • changes in periods

  • constipation or other digestive concerns 

  • muscle or joint pains 

  • sleep disturbance

  • new supplements or medications

A comprehensive lab panel to evaluate fatigue includes: 

  • iron studies: hematology (CBC), ferritin and iron/TIBC (often skipped) 

  • other common nutrient deficiencies: B12 and vitamin D 

  • blood sugars: HbA1C and fasting glucose (or better yet fasting insulin)

  • thyroid levels: TSH and T4 (and sometimes T3 and thyroid antibodies) 

  • testosterone (for people with penises) 

  • and a home sleep apnea test (HSAT) to evaluate for obstructive sleep apnea if other criteria are met (such as: loud snoring, episodes of waking gasping for air, and high blood pressure, especially in patients over 50 years old, and those with obesity)

One test most people don’t need is AM cortisol. A single value doesn’t tell us much or influence treatment planning. The result can actually be influenced by the stress of the blood draw itself, and there’s a lot of

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